Prof Dr. Bernhard G. Herrmann

C4-Professor for Genetics and Director of the Institute for medical Genetics at the Charité, Campus Benjamin Franklin,
Director of the Dept. Developmental Genetics, Max-Planck-Institute for molecular Genetics, Berlin



1983  Diploma in Biology (University Würzburg)
1987  PhD in molecular Genetics (EMBL Heidelberg)
1987-1988  EMBO fellow at the National Institute for Medical Research, London
1989-1994  Group Leader at the MPI of Developmental Biology, Tübingen
1994-2003  Senior Scientist (C3) at the MPI of Immunobiology, Freiburg
2003  Appointment as Professor for Genetics and Director of the Institute for medical Genetics at the Charité, Campus Benjamin Franklin, Member of the Max-Planck-Society and Director of the Dept. Developmental Genetics, Max-Planck-Institute for molecular Genetics, Berlin

Contact Information

Charité - Direktor des Institut für medizinische Genetik der Charité-Campus Benjamin Franklin
c/o MPI für molekulare Genetik
Ihnestraße 63-73
14195 Berlin

Phone: +49 30 841 313 44
email:bernhard.herrmann@charite.de
www:http://www.molgen.mpg.de/~abt_herrmann

Research Interests

Our long-term goal is to understand the genetic basis of organ development in the mouse, as model for the human. High-resolution expression analyses of thousands of genes in the mouse embryo form the basis for establishing expression catalogues reflecting the molecular anatomy of the embryo. Such catalogues serve as resources for resolving particular questions about organisation, pattern formation and organogenesis in the embryo. Bioinformatic means are utilized to order defined gene groups (co-expression groups) into regulatory networks, which are subjected to experimental verification in the mouse embryo and in cell culture systems. Presently our focus is on the epilthelio-mesenchymal transition (EMT) in mesoderm formation, a process highly relevant to metastasis formation, and on the formation and patterning of presomitic mesoderm. Knowledge of the genetic control of developmental processes is applied to tissue engineering in vitro.
Another topic of our work is the molecular genetic investigation of the phenomenon of transmission ratio distortion in the mouse, the unequal transmission of genetic traits to the offspring.

For a more details see http://www.molgen.mpg.de/~abt_herrmann