Module
One:
Molecular Mechanisms of Disease |
Prof. Dr.
Schäfer |
| Module one begins with an introduction to immunology,
a subject of great relevance to all aspects of molecular medicine.
Further topics of instruction include molecular mechanisms
underlying deregulated cell cycles, solid tumors, and leukemia.
Students then go on to study selected aspects of cardio-vascular
medicine. The module concludes with an examination of molecular
mechanisms associated with hereditary cancers. During the laboratory
portion of this module, students work in groups of two or three
and learn how to apply relavent laboratory techniques. |
Module Two:
Maintenance and Integrity
of the Endocrine System |
Prof. Dr. Köhrle |
| Module two begins with instruction
on the development and organization of the endocrine system
and includes topics such as the biosynthesis, secretion, and
action of hormones, as well as hormonal signal transduction
and feedback regulation in metabolism. The course then goes
on to examine the molecular basis of interactions between the
endocrine, neuronal, and immune networks. Module two concludes
with an in-depth study of the molecular basis of mono- and
polygenic endocrine disorders. The laboratory portion of this
module focuses on teaching methods of research in molecular
endocrinology. |
Module Three:
Development and Genetics |
Prof. Dr. Mundlos |
| Module three begins with an examination
of patterning and morphogensis. Students then go on to study
early organogenesis and afterwards are well prepared to focus
on the molecular signal transduction specific to this process.
Insect and animal models are examined throughout the laboratory
portion of this module to practically investigate the theoretical
topics considered. The module concludes with curriculum and
laboratory techniques relevant to human mutational mechanisms
leading to disease. |
Module Four:
Functional Genomics |
Prof. Dr. Herzel |
| Module four is divided into three
sections; Bio-informatics; High throughput technologies and
systems biology; and Population Genetics. Specific topics covered
include genomes and statistics, transcriptomics, and proteomics.
The laboratory portion of the module consists of computer exercises,
some of which students conduct individually, others of which
are conducted in small groups, or by the group as a whole. |
Module Five:
Infection and Pathogens |
Prof. Dr.
Krüger |
| Module five focuses on infectious
diseases such as tuberculosis, influenza, and malaria. Here
students concentrate on the molecular basis of interactions
between pathogens and their hosts, as well as epidemiology.
Students engage in both the practical and theoretical study
of virology, bacteriology, and the immunology of infectious
diseases. |
Module Six:
Therapeutic Research
and Development |
Dr. Antje Ludwig |
| After having explored the theoretical
aspects of molecular medicine, as well as many of the related
research strategies, module six takes students directly into
the clinic. Here they have the opportunity to witness and investigate
the application of the theories and research methods they learned
in previous modules. Clinical studies are the general theme
of this module, and will be explored specifically through lectures
on pharmacology, and factors involved in the design of clinical
studies, as well as by focusing on current case studies related
to diseases studied in previous modules. |